Publications

 

22. Plakoglobin and HMGB1 mediate intestinal epithelial cell apoptosis induced by Clostridioides difficile TcdB
Yingxue Li, Wei Xu, Yutian Ren, Hung-Chi Cheung, Panpan Huang, Guneet Kaur, Chih-Jung Kuo, Sean P. McDonough, Susan L. Fubini, Stephen M. Lipkin, Xin Deng, Yung-Fu Chang*, & Linfeng Huang*
posted on BioRxiv, Jul 2021.
Link to the article

21. Absolute quantification and single-cell dose-response of cytosolic siRNA delivery
Hampus Hedlund, Hampus Du Rietz, Johanna Johansson, Wahed Zedan, Linfeng Huang, Jonas Wallin, & Anders Wittrup
posted on BioRxiv, Apr 2021.
Link to the article

20. Profiling MicroRNAs with Associated Spatial Dynamics in Acute Tissue Slices
Kai Xie, Zixun Wang, Lin Qi, Xi Zhao, Yuan Wang, Jin Qu, Ping Xu, Linfeng Huang, Wenjun Zhang, Yang Yang*, Xin Wang*, & Peng Shi*
ACS Nano, Mar 2021, 23;15(3):4881-4892
Link to the article

19. Combined inhibition of RNA polymerase I and mTORC1/2 synergize to combat oral squamous cell carcinoma
Shanwei Shi, Huigen Luo, Lihong Wang, Hua Li, Yujie Liang, Juan Xia, Zhi Wang, Bin Cheng, Linfeng Huang, Guiqing Liao, & Baoshan Xu
Biomedicine & Pharmacotherapy, https://doi.org/10.1016/j.biopha.2020.110906Get, Nov 2020
Link to the article

18. High-efficiency cellular reprogramming by nanoscale puncturing
Wang Yuan, Wang Zixun, Xie Kai, Zhao Xi, Jiang Xuezhen, Chen Bing, Huang Linfeng, Zhang WenJun, Yang Yang, & Shi Peng
Nano Letters, https://doi.org/10.1021/acs.nanolett.0c01979, Jun, 2020.
Link to the article

17. Intracellular Biopsy based microRNA Profiling for Dissecting the Temporal Dynamics of Cellular Heterogeneity
Zixun Wang†, Lin Qi†, Yang Yang†, Mingxing Lu, Kai Xie, Xi Zhao, Elvis Hung Chi Cheung, Xuezhen Jiang, Wenjun Zhang*, Linfeng Huang*, Xin Wang*, & Peng Shi*
Science Advances, 6:eaba4971, Jun 2020.
Link to the article

16. Tombusvirus p19 captures RNase III-cleaved double-stranded RNAs formed by overlapping sense and antisense transcripts in E. coli
Linfeng Huang*, Padraig Deighan, Jingmin Jing, Yingxue Li, Hung-chi Cheung, Elaine Lee, Shirley S. Mo, Heather Hoover, Sahar Abubucker, Nancy Finkel, Larry McReynolds, Ann Hochschild, & Judy Lieberman*
mBio 11(3):e00485-20, Jun 2020 and bioRxiv
Link to the article
Datasets for this paper

15. Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b
Luyen Tien Vu†, Boya Peng†, Daniel Xin Zhang, Victor Ma, Camille A. Mathey-Andrews, Chun Kuen Lam, Theodoros Kiomourtzis, Jingmin Jin, Larry McReynolds, Linfeng Huang, Andrew Grimson, William C. Cho, Judy Lieberman, & Minh TN Le
Journal of Extracellular Vesicles, Apr 2019, 8(1), 1599680, doi:10.1080/20013078.2019.1599680.
Link to the article

14. Self-assembled lipid nanoparticles for ratiometric codelivery of cisplatin and siRNA targeting XPF to combat drug resistance in lung cancer
Cai Li†, Tianzhong Li†, Linfeng Huang*, Mengsu Yang*, & Guangyu Zhu*
Chemistry - An Asian Journal, Mar 2019, 14(9):1570-1576.
Pubmed

13. Autophagy inhibitor Vacuolin-1 interferes with lipid-based small interference RNA delivery
Tianzhong Li, Jianbo Yue, Linfeng Huang*, & Mengsu Yang*
Biochemical and Biophysical Research Communications, Mar 2019, 510: 427-434.
Link to the article

12. Milligram scale production of potent recombinant small interfering RNAs in Escherichia coli
Guneet Kaur, Hung-chi Cheung, Wei Xu, Jun Vic Wong, For Fan Chan, Yingxue Li, Larry McReynolds, & Linfeng Huang*
Biotechnology and Bioengineering, Sep 2018, 115(9):2280-2291.
Pubmed
Read only version

11. Regeneration of Cortical Tissue from Brain Injury by Implantation of Defined Molecular Gradient of Semaphorin 3A
Zhen Xu, Wei Wang, Yutian Ren, Wenchong Zhang, Peilin Fang, Linfeng Huang, Xin Wang, & Peng Shi
Biomaterials, Mar 2018, 157, 125-135.
Pubmed

10. Production of highly potent recombinant siRNAs in Escherichia coli 
Linfeng Huang*
 & Judy Lieberman*
Nature Protocols, Dec 2013, 8(12), 2325-2336.
Pubmed

9. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria 
Linfeng Huang
, Jingmin Jin, Padraig Deighan, Evgeny Kiner, Larry McReynolds, & Judy Lieberman
Nature Biotechnology, Apr 2013, 31, 350–356 (commented in “Renewable RNAi” of the same issue; highlighted in SciBX, Mar 2013, 6(11))
Pubmed

8. Nucleotide bias of DCL and AGO in plant anti-virus gene silencing 
Thien Ho, Liang Wang, Linfeng Huang, Zhigang Li, Denise W. Pallett, Tamas Dalmay, Kazusato Ohshima, John A. Walsh, & Hui Wang
Protein & Cell, Sep 2010, 1(9), 847-858.
Pubmed

7. An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II
Linfeng Huang
, Alexandra M E Jones , Iain Searle, Kanu Patel, Hannes Vogler, Nina C Hubner, & David C Baulcombe
Nature Structural & Molecular Biology, Jan 2009, 16(1), 91-93
Pubmed

6. Analyses on mutation patterns, detection of population bottlenecks, and suggestion of deleterious-compensatory evolution among members of the genus Potyvirus
H. Wang, L. F.  Huang, & J. I. Cooper
Archives of Virology, Aug 2006, 151(8):1625-33
Pubmed

5. Quantitative in situ assay of salicylic acid in tobacco leaves using genetically modifiedAcinetobacter sp. ADP1 biosensor
Wei E. Huang, Linfeng Huang, Martin Naylor, John P. Carr, Yanhong Li, Andrew C. Singer, Andrew S. Whiteley, & Hui Wang
The Plant Journal, Jun 2006, 46(6):1073-1083
Pubmed

4. Within-population variation in hybridisation and transgene transfer between wild Brassica rapa and Brassica napus
D.W. Pallett, L. Huang, J.I. Cooper, & H. Wang
Annals of Applied BiologyApr 2006, 148(2):147-155
link

3.  The complete genome sequence, organization and affinities of carrot red leaf virus
L. F. Huang, Naylor, M., Pallett, D.W., Reeves, J., Cooper, J.I., & Wang, H
Archives of Virology, Sep 2005, 150(9):1845-55
Pubmed

2. Chromosomally located gene fusions constructed in Acinetobacter sp. ADP1 for environmental detection of salicylate
Wei E. Huang, Hui Wang, Hongjun Zheng, Linfeng Huang, Andrew C. Singer, Ian Thompson, & Andrew S. Whiteley
Environmental Microbiology, Sep 2005, 7(9):1339-48
Pubmed

1.  Heterogeneity in codon usages of Sobemovirusgenes
H. Zhou, H. Wang, L. F. Huang, M. Naylor, & P. Clifford
Archives of Virology, Aug 2005, 150(8):1591-605
Pubmed

                                                            Book chapter

1. RNA Interference Technology
Wei Xu, Xuezhen Jiang, & Linfeng Huang
Comprehensive Biotechnology, Vol. 5, Moo-Young, M., Ed., Elsevier: Pergamon, 2019; pp 560–575. ISBN: 9780444640468.
Link to the book

 

       
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